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Most participants tolerated the medication well by the end of the study period

Despite the cancer cases recorded with the use of semaglutide, other factors may have contributed to cancer development with no association with semaglutide [129]

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These studies (called the STEP Trials) found that Wegovy led to significantly more weight loss (16% weight change) over 68 weeks compared to people taking a placebo drug (5.7% weight change)