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Follow-up appointments occur monthly to assess tolerance, adjust doses, and monitor weight loss progress

Further, oral formulations have been more associated with nausea and vomiting than others

Sometimes

Accordingly, in vitro and ex vivo studies have shown that exposure to saxagliptin (135, 136) but not sitagliptin (136), results in altered cardiac electrophysiology and is associated with impaired cardiomyocyte contractility

It helps improve blood sugar control in adults when used in conjunction with diet and exercise

And as in the case of my patient Megan, who walked into my office long ago with a dire rare disease, the use of glucagon-like peptides--which are powerful gut hormones--should not be cavalier.