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Hepatic impairment: Albumin binding and peptide catabolism may be affected in individuals with significant liver disease, though retatrutide-specific data are lacking

Starting at a lower dose and gradually titrating upwards, as recommended in the Summary of Product Characteristics (SmPC), helps minimise these effects

How to Safely Switch from Semaglutide to Tirzepatide Step 1 Consultation & Review The process begins with a thorough consultation

Sometimes the effectiveness is in the adaptation itself

Consider administering your dose at the beginning of your luteal phase when side effects are more likely, allowing your body to adjust

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