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Exenatide, specifically, was found to reduce oxidative stress and the expression of numerous pro-inflammatory cytokines, such as, for example, monocyte chemoattractant protein 1 (MCP-1), Tumor Necrosis Factor alpha (TNF-alpha), and Interleukin-1 beta (IL-1 beta), in obese patients [31,32,33]
10.1161/STROKEAHA.112.659656 135
We spent years building systems and quality standards, making sure we could scale while maintaining clinical integrity, Heckmann says
