does semaglutide build up over time Once-weekly 7·2 mg in adults with obesity (STEP UP): a randomised, controlled, phase 3b trial Semaglutide results week by week:

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In riskmodeling work, it cut 10year CV risk by roughly 2.4% absolute, compared with about 1.4% for semaglutide, mainly because it drops BMI and systolic blood pressure more

The figures below are the trial rates from each drugs label

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