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While Ozempic isnt FDA-approved for weight management, its active ingredientsemaglutidehas been well-studied for weight loss

There have been postmarketing reports of worsening renal function in patients taking sitagliptin with or without metformin, including acute renal failure, sometimes requiring dialysis

Exclusion criteria: Some people may not be eligible to join certain trials if they take certain medications or have certain health conditions or risk factors

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Wegovy requires gradual dose titration over several months, with significant weight loss generally observed after 36 months of treatment at the maintenance dose