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Weight loss rates will slow down as you approach that threshold, and then potentially level off

However, the exaggerated effect of GLP-1 on postprandial insulin secretion in surgical subjects is not significantly different in those with and without recurrent hypoglycaemia. This means that additional factors are probably involved in the hypoglycaemic response seen in some GB patients

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Steinert RE, Luscombe-Marsh ND, Little TJ, Standfield S, Otto B, Horowitz M et al

Compared with other second- or third-line glucose-lowering medications, the GLP-1RAs demonstrated a lower rate of adverse CVEs, including heart failure (HR 0.88