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Studies in PCOS women note increased ovulation and induction of pregnancies after weight loss with these agents

2014 doi: 10.1097/DAD.0000000000000243

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Regarding meals, avoiding large portions close to bedtime and allowing at least three hours between the last meal and sleep can reduce gastrointestinal discomfort that might disturb rest

Understanding how these three signalling axes interact is central to current metabolic research and forms the primary basis for ongoing investigational study of this compound