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Endocr Pract 2017;23:8999.ArticlePubMed 107

In total, GLP-1 drugs have generated a cumulative $71 billion in the U.S

Twelve weeks of exenatide treatment increases [(18)F]fluorodeoxyglucose uptake by brown adipose tissue without affecting oxidative resting energy expenditure in nondiabetic males

Serious risks include pancreatitis and a potential risk of thyroid C-cell tumors

Reduce la secrecin de glucagn (una hormona que aumenta el nivel de azcar en sangre)

The treatment of type 2 diabetes requires positive modulation of GLP-1R to inhibit glucagon secretion and stimulate insulin secretion in a glucose-dependent manner