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AGREE is quantitative greenness assessment tool as it represents the overall score of the method at the center of the graph ranging from 0 to 1 [32]

Since obesity is associated with higher oestrogen levels (due to peripheral conversion of androgens to oestrogen in adipose tissue), significant weight loss might theoretically influence hormone-dependent conditions

This integrated approach prioritizes safety and precision in treatment selection

Obesity not only significantly increases the risk of developing T2DM but also exacerbates disease severity, with obese individuals being approximately seven times more likely to develop diabetes than those with a normal body weight (22)

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