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For physicians practicing functional and anti-aging medicine, the critical metric is the improvement in underlying cardiovascular and metabolic markers

[DOI] [PubMed] [Google Scholar] 210.Layer P., Holst J.J., Grandt D., Goebell H

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In individuals with obesity without T2DM, SURMOUNT- 1 evaluated the safety and effectiveness of tirzepatide 5, 10, and 15 mg once weekly in comparison to a placebo when paired with a 500 kcal/day deficit diet and recommendations for 150 min of weekly exercise [118]

That leads to benefits in cholesterol levels, lowered bodily inflammation, and other mechanisms that help with heart health. Dr

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