glp 1 vs 2 What is the Difference Between GLP-1, GLP-2, and GLP-3? Current Insights, Advantages and Challenges

(1989) Glucagon antagonists: contribution to binding and activity of the amino-terminal sequence 1-5, position 12, and the putative alpha-helical segment 19-27

Exenatide (EC 50 = 0.60 nM, E max = 125%) and liraglutide (EC 50 = 1.8 nM, E max = 117%) were 380- and 130-fold more potent, respectively, and caused somewhat greater receptor internalization relative to PF-06882961 (Table S5)

Patients with poorly controlled diabetes are at increased risk of candidal infections, particularly vulvovaginal candidiasis in women and balanitis in men

Pemvidutide: GLP-1/glucagon dual receptor agonist

Health Technol Assess (2005) 9(26):1134

The GLP-1 peptide interacts with the receptor via several polar and hydrophobic interactions (see Figure 5)