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The growing prevalence of metabolic disease, CKD, and ASCVD have prompted investigation into the role of GLP-1R agonists in mitigating cardiovascular and metabolic risks, particularly within the framework of Cardiovascular-Kidney-Metabolic (CKM) Syndrome, irrespective of diabetic status

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Ciarmiello A, Giovannini E, Riondato M, et al

9 This speaks to the extremely fundamental processes affected by GLP-1 drugs

Polyphenols, in particular, have attracted attention due to their antioxidant, anti-inflammatory, antiproliferative, proapoptotic, and gut-modulating properties 1
