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Depending on the drug dose, participants lost between 12 and 20 percent of their body weight, on average

Visible changes: noticeable to people around you, clothing sizes may change

These hormones slow digestion, tell your brain, "I'm full with less food," and help release insulin to clean up the glucose in your blood

It's also important to explain to patients that GLP-1 and GIP medications influence appetite and brain reward pathways, which might contribute to mood fluctuations

Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement
