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Treatment of diet-induced obese mice with sitagliptin (4 g/kg), a DPP-4 inhibitor, significantly reduced the expression of inflammatory genes including monocyte chemotactic protein- (MCP-) 1, IL-6, IL-12(p40), IL-12(p35), and IFN- -induced protein 10 (IP-10) in pancreatic islets and improved glucose-stimulated insulin secretion in isolated islets [19]

#MedicationSafety #PatientSafety #NTIDrugs #Healthcare #Nursing #Pharmacy #QualityCare #ClinicalSafety #DrugSafety #HealthcareProfessionals #DrNareshKumarShringi To view or add a comment, sign in The Union Ministry of Health and Family Welfares immediate nationwide prohibition of 16 Fixed-Dose Combination (FDC) drugs marks a critical milestone in Indias ongoing regulatory shift toward evidence-based medicine and patient safety