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Conclusion: The study reveals significant electrolyte imbalances in patients with T2DM, characterized by reduced sodium and chloride levels and elevated potassium levels compared to healthy controls
Mitigating Side Effects Several strategies have proven effective for managing adverse events: Starting with lower doses (e.g., 0.5 mg) rather than higher doses Implementing gradual dose escalation with adequate time between increases Maintaining patients at current doses longer when side effects emerge Monitoring and providing supportive care for gastrointestinal symptoms[8] These approaches can significantly improve tolerability and adherence to the medication regimen
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The collaborative meta-analysis examined 12
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