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Weight loss itself typically improves GERD over time by reducing abdominal fat and pressure on the lower esophageal sphincter

Obesity independently increases cardiovascular mortality, and weight loss of 5 to 10% yields meaningful reductions in cardiovascular disease risk factors

But easier

If energy has stabilized and nutrition is dialed in, begin gradually adding volume back

118 reported that GLP-1RAs with metformin improved oxidative stress markers, such as IL-6, suggesting a reduction in systemic inflammation

The Food and Drug Administration has approved two treatments Biogens Leqembi and Lillys Kisunla that marginally slow the progression of the illness by targeting the diseases hallmark amyloid plaques in the brain
