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This led to excessive satiety, such that she reduced her daily intake to 300350 Calories due to disinterest in food

Still, liraglutide is soon to be available as a generic, so thats something

Trends in insulin resistance: Insights into mechanisms and therapeutic strategy

shows that in participants with type 2 diabetes mellitus with high cardiovascular risk, those receiving the GIP/GLP-1R dual agonist, tirzepatide, had a significantly lower rate of composite renal endpoints, a significantly slower rate of decline in eGFR and a significantly lower urinary albumin creatinine value compared to those receiving glargine insulin [36]

But the long term consequences are expected to cost far more, research published in JAMA Network Open suggests

Rapid GLP-1-driven weight loss without structured physical activity strips muscle and bone, increasing frailty and hospitalizations. Ken Griffin, CEO, AUSactive (Australias peak body for the exercise and active health sector) Griffin has called for a National Physical Activity Strategy in Australia to ensure exercise is routinely prescribed alongside GLP-1 medications, positioning fitness professionals on par with GPs and pharmacists in patient care
