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Among patients with pre-existing substance use disorder, GLP-1s were tied to fewer hospitalizations, overdoses and deaths related to substance use

Preclinical trials in rodents and nonhuman primates show these medications reduce alcohol intake

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333 The expression of miR-124 is low in UC patients, and in vitro experiments have shown that the upregulation of miR-124 can promote a decrease in proinflammatory cytokines, including IL-17 and IL-6, as well as the chemokine CCL2, which plays a role in alleviating UC