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Treatments that focus on collagen preservation, including retinoid skincare products, biostimulatory injectables, and radiofrequency microneedling, can provide additional advantages for sustaining skin health and postponing facial aging signs [52,55]

Biochem Pharmacol 164:3444 Pereira M, Jeyabalan J, Jorgensen CS, Hopkinson M, Al-Jazzar A, Roux JP, Chavassieux P, Orriss IR, Cleasby ME, Chenu C (2015) Chronic administration of glucagon-like peptide-1 receptor agonists improves trabecular bone mass and architecture in ovariectomised mice

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therefore, although we have shown HbA1c and weight improvements in cohorts switching to semaglutide, these patients may have switched treatment for various reasons other than glycaemic control and weight loss