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[79] Trials for cardiovascular health [edit] In March 2024, the US Food and Drug Administration expanded the indication for semaglutide (brand name Wegovy) to reduce the risk of cardiovascular death, heart attack, and stroke in adults with cardiovascular disease and who are either obese or overweight

This shift manifests as bloating, gas, digestive discomfort , and impaired nutrient absorption

For example, Regeneron recently showed combining its antibody trevogrumab with semaglutide helped preserve lean mass while increasing fat mass loss

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Adding cagrilintide into the mix may potentiate results, though this combination is still under investigation

Nie ZJ, Zhang YG, Chang YH, Li QY, Zhang YL