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[Accessed on 18.4.2015]

Palmer SC, Tendal B, Mustafa RA, et al

It also reduced the insulin area under the curve meaning better glucose handling with less insulin demand

Funding This study was supported by a grant of Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Welfare (HF20C0002), The Basic Science Research Program through the National Research Foundation of Korea, funded by The Ministry of Education (2018R1A6A1A03025108), and the Research Fund of The Catholic University of Korea (2023)

A 2022 warning letter from the Office of Prescription Drug Promotion (OPDP) highlighted an Instagram ad posted by the company that reportedly made, false or misleading claims and representations about the benefits and risks of Trulicity. It found that the company minimized the risks and overemphasized the benefits of the drug

CVOTs cardiovascular outcome trials, T2DM type 2 diabetes mellitus, CVD cardiovascular disease, HF heart failure, CKD chronic kidney disease, HbA1c glycated hemoglobin, eGFR estimated glomerular filtration rate, PCI percutaneous coronary intervention, CABG coronary artery bypass graft, GLP-1R GLP-1 receptor, T1DM type 1 diabetes mellitus, GLP-1RAs glucagon-like peptide-1 receptor agonists, DPP-4i DPP-4 inhibitor, HR hazard ratio, CI confidence interval Except for ELIXA and EXSCEL [56, 59], all other major CVOTs point towards cardiovascular benefits of GLP-1RAs [53, 54, 61, 63, 6668]
