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Description
Please reference the FDA-approved Prescribing Information and Information for Patients

Efficacy and safety of LY3298176, a novel dual GIP and GLP1 receptor agonist, in patients with type 2 diabetes: a randomised, placebocontrolled and active comparatorcontrolled phase 2 trial

This reframes GLP-1RAs from a treatment course to a long-term management strategy

Safety and tolerability of RYBELSUS were evaluated across 10 different clinical trials 1-4,a Safety and tolerability of RYBELSUS were evaluated across 10 different clinical trials 1-4,a The most frequently reported adverse reactions were GI disorders, including nausea, abdominal pain, and diarrhea Nausea, vomiting, and/or diarrhea occurred mostly during dose escalation 4% and 8% of patients discontinued RYBELSUS 7 mg and 14 mg, respectively, due to GI adverse reactions, compared to 1% of patients receiving placebo GI=gastrointestinal

A novel adipokine CTRP1 stimulates aldosterone production

For plateau management strategies, see our guide on breaking through Ozempic plateaus
