glp 1 agonist ilaçlar İlaçları Nedir? Etkileri, Kullanım Alanları ve Yan Etkileri Yeni zayıflama ilaçları (GLP-1 reseptör

10.1016/j.jdiacomp.2009.01.004 112 MariA.SallasW

Employing preclinical, ex vivo, in vivo, and in vitro model systems investigators determined that GLP-1 agonists exert anti-inflammatory and immune modulating effects through their effects on macrophages (reduced interleukin [IL] 1, IL-6, tumor necrosis factor [TNF], and C-X-C motif chemokine ligand [CXCL]), T and B lymphocytes (reduced cluster of differentiation [CD] 4 cells), monocytes (increased IL-10), mononuclear cells (decreased monocyte chemoattractant protein [MCP]1, cell death protein [PD],, CD4 and CD8 T cells) [5155]

Some gut hormones also lower glucagon levels

Graphical abstract Fig

Vniant MM, Lu SC, Atangan L, Komorowski R, Stanislaus S, Cheng Y, et al

doi: 10.1074/jbc.M500540200 115 TrmperATrmperKTrusheimHArnoldRGkeBHrschD