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Description
PMID: 8538742
GLP-1, however, engages the GLP-1R/ERK1/2/HDAC6 axis to modulate downstream transcriptional activity, it lowers intracellular ROS, reduces Akt and ERK1/2 phosphorylation, restores HDAC6 expression, and thereby alleviates endothelial dysfunction and excessive autophagy (Zummo et al., 2017)

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Conversely, if a patient's blood glucose is greater than 250 mg/dL prior to exercise, exercise should be approached with caution

Several possible reasons may explain the benefit

One study explained that while the patient followed current guidelines, shortly prior to extubation, the patient developed large-volume emesis with contents consistent with food the patient reported eating several days prior (Beam and Hunter Guevara 2023)