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Previous study also shows that upregulation of ITPR1 expression enhances autophagy, thereby sensitizes paclitaxel cytotoxicity (Xu et al., 2019b), suggesting a favorable prognosis in human cancer

PLoS ONE 8 , e69824 (2013)
Despite existing limitations, spontaneous reporting may be the best way to find rare AEs

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Providers view GLP-1 therapy as a clear medical necessity