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Description
Orforglipron is still in phase 3 clinical trials and is not approved for prescription in the UK or anywhere globally

Truncated Glucagon-Like Peptide I, An Insulin-Releasing Hormone From the Distal Gut

It was used in a once-daily multiple ascending dose phase Ib clinical trial and a 41-day phase IIa trial in overweight and type 2 diabetic patients, and the general safety and tolerability of MEDI0382 were established, as was its placebo-corrected efficacy in reducing fasting blood glucose (1.7 mmol/L), postprandial glucose excursions following a mixed meal test (22.6% area under the curve 04 hours), body weight (2.1 kg), and liver fat (19.6%)

Follow-ups Follow-up visits are scheduled weekly, bi-weekly, or monthly depending on your needs and preferences

Stuber et al., 2025)

doi: 10.1111/liv.14065
