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Dehydration can mask genuine weight loss (due to fluid retention) and amplify side effects like nausea or constipation, which discourage adherence

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Albeit long overdue, this progress offers real reason for hope

Gould notes, they havent been fully demonstrated in human tissue or large-scale trials. Whats more, it can be hard to tease out the influence of GLP-1s from that of age and hormones, which can similarly undermine our tissues

Purtell identifies several common factors that patients may consider as barriers to their weight loss goals
