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These changes were statistically significant and potentially clinically meaningful, as even modest blood pressure reductions of this magnitude are associated with reduced cardiovascular event rates at a population level

A 2024 study in Translational Psychiatry used positron emission tomography (PET) imaging to measure dopamine transporter binding in the striatum of adults with obesity before and after 12 weeks of semaglutide treatment

STEP 5: sustained 15.2% at 104 weeks [2]

Data and documents, including the study protocol, statistical analysis plan, clinical study report and blank or annotated case report forms, will be provided in a secure data-sharing environment