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Early-stage studies revealed an initial increase in 24 h ambulatory SBP, which subsided over time, leading to a net reduction in SBP

Their findings, however, proved inconclusive

doi: 10.2337/db14-1718

Microdosing advocates claim it can help with weight loss by reducing cravings, better metabolic health, reduce inflammation, enhance mood and cognitive function, and even potentially improve longevity, all while coming with fewer side effects and being more affordable than larger doses

Additionally, the substitution of arginine at positions 2 and 13 with 2-aminoisobutyric acid (Aib) increases its resistance to DPP-4 and enhances its ability to bind to albumin, thereby improving its stability and half-life

GLP-1 treatments, such as liraglutide and semaglutide, work by curbing appetite and slowing digestion