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For GLP-1 users, the magnitude of lean body mass loss can be on par with the loss experienced after bariatric surgery, cancer treatment, or 10 years of ageing

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In a 2023 animal and laboratory study, researchers suggested that GLP-1 medications could have the following benefits for people with UC: lowering the levels of proinflammatory mediators chemicals that cause inflammation preventing certain important proteins and pathways in the body from becoming overactive, which can contribute to UC repairing damage to the inner lining of the intestines improving the balance of good bacteria in the gut The researchers suggested that GLP-1 medications may be a promising future treatment for UC

However, for people with significant metabolic dysfunction like type 2 diabetes, the enhanced metabolic benefits might matter