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Annu Rev Med 2023;74:12539

Nutrition, exercise, sleep hygiene, stress management, and behavioural support are all essential
All groups reported the highest incidence of GI events early (within the first 2 weeks) in treatment

The difference between Exendin-4 and Exenatide lies primarily in the replacement of Ala with Valine (Val) at the 19th position and Asn with aspartic acid at the 28th position in Exendin-4

Long-term outcome data, particularly on cardiovascular events, is currently stronger for injectable semaglutide thanks to the SELECT trial
