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Like GLP-1, GIP travels through your bloodstream and activates specific GIP receptors in various organs

Since the glucose-lowering effects of GIP have been shown to be impaired in patients with T2D, interest has focused on developing antidiabetic therapies based upon the actions of GLP-1 and GIP, the response to which remains intact. To continue reading Log in or register to continue reading

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The effect was nominally significant for the GIPR/GLP-1R agonist (Beta: 0.35, 95%CI: 0.010.69, P = 0.046), while the associations for the GCGR/GLP-1R agonist (Beta: 0.28, 95%CI: 0.070.49, P = 7.97 10 3 ) and the GCGR/GIPR/GLP-1R agonist (Beta: 0.39, 95%CI: 0.110.66, P = 5.67 10 3 ) remained significant after multiple testing (Fig