which is best tirzepatide or semaglutide vs Tirzepatide vs. Semaglutide: Key Differences

I once sat with a patient who swore her cold from hell was ruining her sleep for a week

The proportion of patients achieving HbA1c of less than 7 % without severe or confirmed episodes of hypoglycaemia and without weight gain was significantly higher with semaglutide at doses of 0.5 mg and 1 mg (up to 66 % and 74 %, respectively) versus patients treated with sitagliptin (27 %), exenatide ER (29 %), insulin glargine (16%), dulaglutide 0.75 mg (44 %) and dulaglutide 1.5 mg (58 %)

Key Differences Although they share broad goals, important differences stand out

Berryman, D

Seek medical advice first if you have kidney disease or have been told to restrict creatine or protein

Zepbound was also FDA-approved in 2024 for moderate-to-severe obstructive sleep apnea in adults with obesity