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GLP-1 patches and oral liquid formulations represent additional delivery innovations that naturally provide more stable drug levels through continuous or frequent dosing

Back Unger, RH, Cherrington, AD (3 Jan 2012) 'Glucagonocentric restructuring of diabetes: a pathophysiologic and therapeutic makeover', Journal Clinical Investigation , 122/1, 4-12

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It is also the simplest amino acid, making it generally well-tolerated with minimal risk of adverse reactions

Specifically, Asp 21P forms a salt bridge with R242 ECL1 , while Trp 25P forms a hydrogen bond with D244 ECL1 and pi-pi stacking with W249 ECL1 , which was stabilized by Phe 22P