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Genetic variants in GLP-1 receptor (GLP1R rs6923761), glucose-dependent insulinotropic polypeptide receptor (GIPR rs1800437), and appetite-regulation genes (FTO rs9939609, MC4R rs17782313) correlate with differential treatment response

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4A, all models performed similarly except SVC

Common adverse effects associated with Ozempic include gastrointestinal symptoms such as nausea, vomiting, diarrhoea, and constipation, particularly during the initial titration phase

In patients taking GLP-1 RAs or similar weight loss medication, wrinkles become more prominent, and the skin starts to sag in areas such as the temples, cheeks, tear troughs, jawline, marionette lines, and nasolabial folds