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Additionally, after 6 months there were reports of some patients with higher BMIs losing 20-30% of their body weight

Change in albuminuria and GFR as end points for clinical trials in early stages of CKD: a scientific workshop sponsored by the national kidney Foundation in collaboration with the US Food and Drug Administration and European Medicines Agency

If you typically eat when stressed, bored, or celebrating, those triggers may persist even as physical appetite diminishes

Sang X, Li S, Guo R, Yan Q, Liu C, Zhang Y, et al

Most patients begin noticing changes within 46 weeks , with steady progress over several months

Common adverse effects include gastrointestinal symptoms such as nausea, diarrhea, vomiting, constipation, and abdominal discomfort, which typically diminish over time