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At the start of your treatment, you may experience significant weight loss, but this can stall as your body adjusts to the medication or your metabolism returns to normal

From 2008-2010, Sanofi-Aventis Acomplia (selective CB1 antagonist) and Abbott Laboratories Meridia (NE/5-HT reuptake inhibitor)--both also designed to suppress appetite--were pulled from the market over similar cardiac safety concerns

Not everyone may experience this effect

3 (1), e001986 (2013)

While these symptoms typically improve over time, they can be challenging for some patients to tolerate, particularly during the initial stages of treatment

Its a very interesting study, said Dr