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Chung EYM, Badve SV, Heerspink HJL, Wong MG (2023) Endothelin receptor antagonists in kidney protection for diabetic kidney disease and beyond

Taking more or less than prescribed can lead to unintended and potentially harmful side effects
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GLP-1 RAs are designed to last much longer, from the time you take one dose until the time the next is due

Roche for example paid $2.7bn to acquire privately held Carmot Therapeutics while AstraZeneca in-licensed an oral drug from Chinas Eccogene for $185m upfront (and $1.8bn of potential milestones)

23 These concerns were, however, largely based on the preclinical data from animal studies

June 15, 2022