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Ozempic, with its active ingredient Semaglutide, is a GLP-1 receptor agonist that supports better insulin regulation and appetite control

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Activation of GLP-1R in the hypothalamic paraventricular nucleus (PVN) triggers an appetite-suppressing response through neural pathways involving corticotropin-releasing hormone (CRH) excitatory neurons (103, 104)

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GLP-1 medications address some of these challenges directly, which is part of why demand for semaglutide and tirzepatide has been particularly strong among adults in their 50s and 60s