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Description
However, despite clear evidence that EC cell-derived 5-HT negatively impacts energy balance and glucose homeostasis, the underlying causes of elevated 5-HT levels with obesity and T2D remain unclear

Phentermine may have a role in specific scenariossuch as short-term use (typically 12 weeks or less) in patients with no cardiac historybut evidence increasingly favors GLP-1 monotherapy as a first-line approach due to better safety margins and sustained weight loss

Improved Blood Sugar Control Its action on multiple hormones helps stabilize blood glucose more effectively than single-target drugs

Gonzlez-Rubio F, Caldern-Larraaga A, Poblador-Plou B, Navarro-Pemn C, Lpez-Cabaas A, Prados-Torres A: Underreporting of recognized adverse drug reactions by primary care physicians: an exploratory study

These side effects mostly show up in the digestive system

METHODS A narrative review was conducted utilizing the PubMed database of literature published in English through November 15, 2024
