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In vivo evidence of the role of GLP-1/GLP-1R is from Glp-1r / mice, which exhibited an increased number of osteoclasts accompanied by greater bone resorption activity and increased expression of osteoclast-related genes

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Recent evidence highlights the direct and indirect anti-inflammatory properties of GLP-1, suggesting a potential additional therapeutic strategy for patients with inflammatory bowel disease (IBD)

Eli Lilly said the oral GLP-1 pill has been shown to reduce hemoglobin A1C levels -- a blood test that shows average blood sugar levels over two to three months -- by an average of 1.3% to 1.8% in people with diabetes

Sensitivity analyses included the following: Exclusion of high risk of bias studies
