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This weeks Dear Laura is about GLP-1s, shame, and the fear of being judged for choosing help.

However, some patients do report irritability, which is most often related to indirect factors such as under-eating, blood sugar fluctuations, sleep disruption, or changes in reward signaling rather than the medication itself.This post explains the science behind these effects, identifies who may be more vulnerable, and outlines practical strategies clinicians and patients can use to reduce risk

PBH is characterized by postprandial hypoglycemia causing neuroglycopenic symptoms of confusion, loss of consciousness, and seizures in a smaller subset of patients

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This review examines its efficacy, safety profile, and compares it to injectable semaglutide, helping to determine its place in weight management strategies

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