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Update methods: Test methods require occasional updates through change management

Novel gut-based pharmacology of metformin in patients with type 2 diabetes mellitus

(Lausanne) 13 , 934775 (2022)

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For example, chitosan, chitooligosaccharides, and chitosan-derivates have demonstrated anti-obesogenic effects through different mechanisms: inhibition of PPAR-, stimulation of glucokinase, reduction of leptin, adiponectin, and resistin levels, inhibition of adipogenesis, lipid metabolism modulation, and suppression of phosphoenolpyruvate carboxylase (Shagdarova et al., 2023)