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In that analysis, patients in the semaglutide group showed improvement from baseline to week 52 in both body weight (mean 8.4% reduction

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14 However, in two studies that included participants not enrolled in the SURPASS and SURMOUNT studies, ie, a large number of individuals who switched from other GLP-1 RAs to tirzepatide, those who transitioned from semaglutide experienced greater weight loss with tirzepatide treatment

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