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And I had patients that I had noticed that when they were living with depression or bipolar illness, if they were obese, if they were diabetic, if they had metabolic syndrome or some condition related to that, they were much more likely to have severe pathology

In fact, ip injection or NTS infusion of ghrelin reduces nausea-related pica by improving gastric motility in rats treated with cisplatin [139,140]

These methods, of course, have pros and cons

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FACT: GLP1 drugs might be key for helping people manage diabetes or lose weight, but they are not magical

In terms of valence (pleasure) and arousal (motivation), GLP-1 lowers the arousal or urgency triggered by food cues while boosting the positive valence of actually eating the food, thereby signaling the brain, "This is enough, youre full." These neuroimaging findings give a concrete mechanism for the subjective reports of reduced cravings on GLP-1 therapy