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doi: 10.1016/S0140-6736(18)32260-8 [DOI] [PubMed] [Google Scholar] 190.Rosenstock J, Wysham C, Fras JP, et al
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The main enzyme involved, dipeptidyl peptidase-4 (DPP-4) also known as CD26, cleaves off the two N-terminal residues resulting in GLP-1 (9-36 amide) which is inactive or acts as an inhibitor at the GLP-1 receptor (23)

Nauck et al., 2014

This is an application that has a completely different magnitude of use rates and thus, overall consequences for long-term side effects

You might also experience a bit of placebo effect
