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Nausea and constipation are the most common early symptoms but improve significantly by week 34 in the majority of users

In addition, a small number of participants were included in this study, which was insufficient to evaluate the effect of OW semaglutide, for example, in relevant subgroups based on body weight or obesity categories in a Korean population

MPS mostly affect the paediatric population and unfortunately about 70% of all affected patients present a neurological involvement with storage also affecting the central nervous system (CNS), where GAG accumulation can seriously affect neurons leading to death through apoptosis or necrosis during the advanced stages of the disease [1]