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The predicted event probabilities for each individual in STEP 1 and STEP 2 were provided by SomaLogic

What are the prescribing criteria for oral semaglutide (Rybelsus) for weight loss in adults, including BMI thresholds, required comorbidities, contraindications, and dosing schedule?

Supervision: [Yanjie Guo], and all authors commented on previous versions of the manuscript

Dehydration can exacerbate nausea levels, so be sure to keep hydrated, plus avoid large meals right after taking this medication as they can worsen other side effects unnecessarily

Ellis, J

Clinical trials show participants achieve sustainable weight loss without requiring extreme calorie restriction, making adherence easier than traditional dieting