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Central obesity may account for most of the colorectal cancer risk linked to obesity: evidence from the UK Biobank prospective cohort[J]

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People with a History of Certain Cancers : Specifically, those with a personal or family history of Medullary Thyroid Carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

It has been shown to reduce body weight by a mean of 15.2% in overweight/obese patients without diabetes, but with the presence of at least one weight-related comorbidity (hypertension, dyslipidemia, CVD) 28

However, no prospective studies have yet evaluated the effectiveness of this strategy to reduce the risk of pulmonary aspiration
